Vitamin C for Male Infertility and Lead Poisoning?

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What’s the medical relevance of vitamin C amongst lead-exposed infertile males? In comparison with controls, lead battery business employees given 1,000 mg of vitamin C each workday for 3 months skilled “a major enhance in sperm motility and sperm rely, in addition to lower in irregular sperm,” and “a major discount within the incidence of sperm DNA fragmentation,” that’s, broken sperm DNA. Okay, however the excellent endpoint could be bouncing child girls and boys. Enter this extraordinary little research from the College of Texas from greater than 30 years in the past.

Twenty-seven males with fertile wives had been trying to have youngsters for years to no avail. Twenty of them got 1,000 mg of vitamin C a day for 2 months, and seven acted as controls and didn’t get any vitamin C. The researchers adopted up on the finish of the 60 days. By then, each single one of many wives of every of the 20 males who had gotten the vitamin C had turned pregnant—20 out of 20! After years of frustration, increase: 100-percent pregnant. What’s extra, not a single one of many wives of males within the management group acquired pregnant. Hardly ever does one see these sorts of black-and-white ends in the medical literature for any intervention.

Is the vitamin C lowering the oxidative stress from the lead, or is it really decreasing the stage of lead? Positive, antioxidant supplementation can have antioxidant results, however it could fail to really decrease lead ranges within the blood. Now, this was in a team of workers who have been respiratory lead day in and day trip, and the way in which vitamin C may fit is by merely blocking the “intestinal absorption of lead.” An earlier research confirmed vitamin C supplementation apparently cut lead ranges by a 3rd inside six months, however that was with a whopping dose of two g with added zinc. One other small research found the identical 30 % drop with simply 500 mg a day, no zinc, and in just one month. However neither of these research had a management group of topics who didn’t take something, so we don’t know if their ranges would have fallen anyway.

Equally, there’s an nearly too-good-to-be-true research on the function of vitamin C in scavenging lead toxicity from “biosystems,” by which they meant youngsters. They acquired 250 to 500 mg a day of vitamin C for just a few months, and shaved hair samples each month noticed as much as a 69 % decline in lead ranges. Researchers repeated it in two different small teams of children and noticed the identical wonderful type of drops in each single youngster. However possibly lead ranges have been simply dropping all through the entire group throughout that point? With out measuring lead ranges in a management group of children not taking vitamin C, we will’t make sure.

As I illustrate from 3:17 in my video Yellow Bell Peppers for Male Infertility and Lead Poisoning?, with eight weeks of vitamin C, lead ranges dropped within the blood and rose within the urine. One may conclude that the vitamin C was pulling lead out of the physique, however the identical factor occurred within the placebo group: Blood ranges dropped, and urine ranges rose. So, it had nothing to do with the vitamin C in any respect. That’s why it’s all the time necessary to have a management group.

The identical applies with research that appeared to point out no profit. For instance, 36 battery manufacturing employees have been studied. Every was given vitamin C, but there was no change of their lead ranges. However, possibly their co-workers suffered an enormous enhance in lead ranges throughout that very same time interval, and the vitamin C was really profitable in protecting the topics’ ranges from rising. You don’t know with no management group.

That’s why research like “The consequences of vitamin C supplementation on blood and hair ranges of cadmium, lead, and mercury” are so necessary. Vitamin C versus an identical-looking sugar capsule placebo. The outcome? The vitamin C failed to assist, which actually put a damper on enthusiasm for utilizing vitamin C for lead poisoning till a now-famous research was revealed in 1999 that confirmed that vitamin C supplementation may lead to a lower in blood ranges. As you’ll be able to see at 4:32 in my video, after 4 weeks of taking a placebo, not a lot change occurred in blood lead ranges within the management group, which is what we’d anticipate. In distinction, the vitamin C group began out at about the identical blood lead stage because the management group, however inside one week of taking 1,000 mg of vitamin C a day, lead ranges dropped 81 %. So, supplementation of vitamin C “could present a cost-effective and handy methodology of decreasing blood-lead ranges, probably by decreasing the intestinal absorption of lead.”

The urine lead ranges didn’t change, so it’s not as if the topics have been excreting extra lead of their urine to convey down their blood ranges. Nevertheless, a lot of the lead in our blood is within the crimson blood cells, that are recycled within the liver and discharged via the bile into the intestine the place the lead may simply get reabsorbed—except, maybe, you’ve acquired a number of vitamin C in there to dam the re-absorption. However 1,000 mg is a number of vitamin C. Would one thing like 200 mg, which is nearly how a lot vitamin C you’d get in an orange and a cup of broccoli or strawberries, work? The researchers examined that, too. The 200 mg group began out the identical because the management and the 1,000 mg group, however blood lead ranges didn’t actually budge. Bummer! So, 1,000 mg appeared to work, however 200 mg didn’t. Isn’t 1,000 mg of vitamin C a bit unnatural, although? The RDA is simply 60 mg. Nicely, really, we could have evolved for tens of millions of years getting nearer to 600 mg a day—ten instances the present RDA—as a result of we have been consuming so many fruits and greens. Okay, however may you attain 1,000 mg of vitamin C with out having to take drugs? Sure! That’s the quantity of vitamin C, for instance, that may be present in three yellow bell peppers.


Different movies in my sequence on lead embody:

Word that there’s nothing particular about yellow bell peppers—aside from their extraordinary vitamin C content material, that’s. I simply used them as a sensible approach to get 1,000 mg of vitamin C in whole-food kind. They’re actually simpler than consuming ten oranges!

Although, keep in mind my video Peppers and Parkinson’s: The Benefits of Smoking Without the Risks? So, one would anticipate to get all the advantages of the 1,000 mg of vitamin C with advantages. Why not simply take vitamin C dietary supplements? See Do Vitamin C Supplements Prevent Colds but Cause Kidney Stones?.

If a whole lot of milligrams a day of vitamin C seems like loads, take a look at What Is the Optimal Vitamin C intake?.

You could be inquisitive about my vitamin C and most cancers sequence:

Lastly, for extra on male fertility, see:

In well being,

Michael Greger, M.D.

PS: Should you haven’t but, you’ll be able to subscribe to my free movies here and watch my reside shows:



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